Today’s bonus episode guest is Dr. Mike Large, director of genomic laboratories at CooperGenomics, which provides PGS and other reproductive genetic testing.
- Tell me a little about yourself and your role at CooperGenomics.
- What is PGS and what was it originally designed to detect?
- What is mosaicism and how is it detected?
- How common is mosaicism?
- How accurate is mosaicism detection? What are the risks in relying on a single biopsy?
- What is the difference between normal, abnormal, and mosaic embryos? Does mosaicism exist on a scale?
- What is the prognosis of transferring a mosaic embryo vs. a normal one, and why? Is it even safe to transfer a mosaic embryo?
- What is the latest research around mosaicism? What future research still needs to be conducted?
- Do you know of any success stories involving mosaic embryos? If so, please tell us a bit about those cases.
- What words of hope would you offer to someone who’s just received a report that either some or all of their embryos are mosaic?