BONUS 292: Future Infertility Research (Part 1)

January 1, 2021

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Today’s bonus episode guest is Dr. Carol Curchoe, the founder of ART Compass, a senior clinical embryologist at a fertility clinic and a board-certified technical supervisor in embryology.

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Dr. Curchoe and Heather discuss the first of the top 10 priorities for future infertility research:

LISTENER QUESTIONS

  • My embryo was abnormal… why did you still freeze it?
  • How do you grade embryos and what does the grade mean?
  • What is the process for transferring gametes from one clinic to another? Is it safe?
  • How long do cryopreserved embryos last?
  • What are the options if I/we no longer wish to store the embryos? How are embryos discarded?

TOP RESEARCH PRIORITIES

  • An article was published in Human Reproduction in November 2020 outlining the top future infertility-related research priorities. Before we dive into the specifics, can you tell us about the study design, methods, and limitations?
  • Research priority #1: What are the causes of implantation failure?
    • A review of the placenta!
  • What is implantation failure or RIF?
    • What is progesterone resistance?
    • What is a shifted window of receptivity?
    • What does decreased integrin expression mean?
    • What are the immune system disturbances that can cause IF?
  • Is there anything else you’d like to add?

WRAPPING UP

  • What words of hope would you offer to infertility warriors about the future of infertility research?

References:

Thanks for listening!

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